Introduction
Genome Technology, Status and Future Directions
November 29, 2022
Guest Speaker, BIOE291
Adelaide Rhodes, Ph.D.,
Senior Bioinformatics Scientist
Assignment before Next Week
Read brief blog post about Alphafold
Computer Set Up for Hands On Practice
- Be prepared to code (i.e., work off a laptop/desktop)
- Account on Tufts HPC
- Confirm you can log in to Open OnDemand
- VPN if accessing the HPC from off campus
- PyMOL
Introduction to AlphaFold2
December 6, 2022
TTS Research Technology Instructors
- Jason Laird, M.S., Bioinformatics Scientist
Goals
- Understand the background of Protein Structure Prediction
- Understand how AlphaFold2 takes a protein sequence and creates a predicted protein structure
- Analyze AlphaFold2 output and determine how well it compares to available structures
- Visualize protein structures in PyMOL
- Optional: Write an AlphaFold2 batch script