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Cas12a Mutant Structural Predictions With AlphaFold2

Materials designed for class CHBE0165 (Biomolecular Engineering and Design) Spring 2024.

Content developed by TTS Research Technology

  • Shirley Li, PhD, Bioinformatician, xue.li37@tufts.edu
  • Jason Laird, MSc, former Bioinformatics Scientist

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Prerequisites

Contents

  1. Run AlphaFold2 on Tufts HPC CLI
  2. Run AlphaFold2 on Tufts HPC with Open OnDemand and Accuracy Assessment
  3. Vizualize Predicted Structure with PYMOL
  4. Slides for this lecture is here.

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